Methylthiouracil
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English name Properties Thiourea antithyroid drugs mainly inhibit the synthesis of thyroxine. Its mechanism of action is by inhibiting thyroid endoperoxidase, preventing the oxidation of iodide taken into the thyroid gland and the coupling of tyrosine, thus hindering the synthesis of thyroxine and triiodothyronine. This product does not block the release of stored thyroid hormone, so significant clinical effects will occur only after the thyroid hormone has been eliminated from the body and the concentration in the circulation decreases. In addition, propylthiouracil also inhibits deiodination production in peripheral tissues
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. r, , ( ) . br , r
methylthiouracil